What Genomics Can Do For Your Practice

Genomic medicine is transforming healthcare, and enabling an entirely new business model for physicians and nutrition professionals. Typical one-size-fits-all, trial and error, and crisis-driven approaches to healthcare are expensive, inefficient, and out-of-date. Effective prevention strategies are limited. More personalized approaches to healthcare are growing, but they still often lack precision. Patients are becoming more involved in …

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Vaccinomics: A Personalized Approach

Many factors can play a role in determining the effectiveness of vaccines, including the interplay between genomics, epigenetics, and the microbiome. The study of how these factors influence how a person develops immunity from a vaccination is called Vaccinomics, and may help revolutionize our approach to this approach to population-based health. Twin studies have shown …

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Genomics and Personalized Wellness: Setting the Record Straight

Are you a corporate executive, medical or HR director who is considering or interested in providing genomic testing to your employees? Do you have concerns, are confused or need clarity about which DNA-based testing will provide your company and employees the most value? We can help. Having pioneered genomic testing in the corporate workplace over …

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Pharmacogenomics

Adverse drug reactions, over prescribing, under prescribing, and trial-and-error attempts to identify appropriate medications puts patients at risk and wastes billions of dollars every year. Half of the U.S. adult population uses at least one medication on a regular basis, and 15% are using five or more. Adverse drug events among adults are estimated by the …

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Genomic Testing & Personalized Medicine Support Workplace Wellness

You may have noticed the terms personalized medicine, individualized or personalized dietary plans, nutrigenomics, and precision medicine cropping up in the news, at professional conferences, or even among conversations with family and coworkers. All these refer to a new technology called genomics, developed as part of the Human Genome Project. But what do they mean? …

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The “Omics” Revolution is Changing Healthcare

The “Omics” revolution represents truly personalized, precision medicine. The term “omics” has penetrated virtually every field of medicine – from cancer treatment, to medication management, to personalized diet and lifestyle interventions for chronic disease treatment and prevention. In this article, we will provide an overview of some of the ways genomics is being used today …

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Beginner’s Guide To Genomic Medicine

Genomics studies the interactions of the environment and our DNA. With 20,000–25,000 genes that contain over 3 billion base pairs of DNA, our genome provides the blueprint for everything that happens in our bodies. Genomic Tests Genomic testing starts with collecting a small DNA sample with a simple cheek swab. At our certified laboratory, we detect …

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Genomic Medicine Is Precision Medicine

Analysis of a patient’s unique DNA profile provides detailed insight into the root causes of disease, guiding individual paths to optimal health. Genomics is revolutionizing an ever growing number of medical disciplines, leveraging vast amounts of previously unavailable data to improve diagnosis, prevention and treatment strategies tailored to each individual’s unique biochemistry. This is precision …

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Nutritional Genomics

Have you ever asked or been asked these questions, and have been uncertain as to the answer? Why are some people more susceptible to diabetes or obesity? Why do certain foods help some people more effectively than others? Why do nutritional requirements vary from person to person? The answer lies in our genes. Genomic analysis …

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Introduction to Genomics

A genome is a complete set of genetic instructions. With 20,000–25,000 genes that contain over 3 billion base pairs of DNA, our genome provides the blueprint for everything that happens in our bodies. Genomics identifies and analyzes variations in the DNA called single nucleotide polymorphisms (SNPs, pronounced “snips”). Over time, a small change can have a …

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Migraines

Migraine headaches are one of the most common neurological disorders worldwide, affecting between 10–20% of the adult population. Migraines are caused by an interaction between environmental and genetic factors. Genomic studies have dramatically increased our understanding of migraine pathophysiology. Evaluating a person’s genomic profile identifies susceptibility to developing migraines, and enables evidence-based, personalized prevention and treatment strategies. …

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Weight Management

Obesity is a growing public health concern both in the U.S. and worldwide: One out of every three U.S. adults are obese Nearly 20% of U.S. children struggle with obesity Genetic contribution to obesity is estimated at 40–70% Eating fresh, whole foods, reducing consumption of sugar and processed foods, exercising regularly, and drinking plenty of water all can help …

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Men’s Health

Heart disease, diabetes, prostate cancer, and neurodegenerative diseases rank at the top of men’s health concerns. A multitude of factors are involved, and the fact that every person is genetically different adds to this complexity. Analyzing a patient’s unique genomic profile is a highly-effective first step in being able to personalize prevention or treatment. Cumulative estrogen exposure can increase the risk …

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Comprehensive Testing For Personalized Answers

Our genomic testing can evaluate predispositions for hundreds of health conditions, and processing of more than 200 medications. We design our Ultimate Wellness nutritional genomic test to target a wide array of biological areas and metabolic pathways associated with health and disease. Our comprehensive, gender-specific reports provide DNA-directed guidance for diet, exercise and nutritional supplements, …

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Women’s Health

Estrogen metabolism is one of the most important factors influencing a women’s health. The majority – 70% – of breast cancer cases are estrogen-induced. Only 10-15% of all cases are due to hereditary gene mutations such as BRCA1 or BRCA2. Understanding a woman’s genomic profile associated with estrogen detoxification can provide personalized strategies to improve …

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Depression, Anxiety & Addictions

Mental health issues are a silent epidemic. Drug and alcohol addiction afflicts one in ten Americans. Major depressive disorder and anxiety disorder impact 6–7% of the U.S. population. Emotional health involves complex interactions between an individual’s neurogenetic chemistry and the environment. Contributing factors include neurotransmitter imbalances, mood disorders, inflammation, exaggerated stress response, response to trauma, cognitive flexibility, and …

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Personalized Nutrition

What Does My Body Really Need? Certain general guidelines apply to a healthy lifestyle—eat lots of fresh foods, reduce the intake of sugar and processed foods, and drink plenty of water. But any one-size-fits-all dietary program will inevitably fall short of providing the nutritional needs unique to your personal genetic makeup. Humans are 99% genetically identical. It’s …

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Healthy Aging

Human longevity is a polygenic trait, meaning multiple genes are responsible for overall health. The Human Genome Project advanced medical science in the understanding of which genes are involved in specific metabolic or disease processes. Genomics has improved our understanding of the aging process and enabled the development of personalized interventions that help people lead longer, healthier, more vibrant and active lives. Environmental …

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Athletic Performance

Aerobic Performance, Nutrition, Injury + Recovery People who are physically active tend to live longer. Regular exercise is important for stress reduction, weight management, brain functioning, detoxification, and much more. There are more than 70 genes linked to athletic performance for both the elite athlete as well as the weekend warrior. Genes can impact the risk of …

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Cancer Susceptibility

1.5 million people are diagnosed with cancer in the United States every year. By 2020, this number is expected to increase to 2 million, overtaking heart disease as the leading cause of death in America. The National Institute of Health has identified that—without ever being aware of the threat—individuals resist an average of 6–7 cancer …

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The Path To Personalized Medicine

This interview with Karen Rider initially appeared in The Progressive Physician. If doctors could magically peer into the genomics of each patient to prescribe the right treatment, at the right time, in the right amount, delivering personalized medicine would be easy as it is effective. Genomic testing and analysis, and translation of that data into …

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Detoxification

According to the Natural Resources Defense Council, more than 80,000 toxic chemicals have been developed in the last century. And most of them have not been evaluated for their impact on human health. These toxins in our food and the environment can overwhelm the natural detoxification process. When this happens, disease can result. Conditions including …

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Risk Predicting Genomic Models

MTHFR (methylenetetrahydrofolate reductase) is part of the folate pathway implicated in the autism spectrum, neurodevelopmental disorders, mood disorders, cervical dysplasia, cardiovascular disease, several types of cancer, and epigenetic modification of DNA. Genomic research over the last 10 years has primarily focused on MTHFR, however, other genes encoding enzymes downstream from MTHFR in the transmethylation (methyl …

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Mental Health–A Systems Approach

How Can Psychiatry Address Biochemical, Nutritional & Neurological Issues?   Functional genomics is an integral part of personalizing approaches to any health condition, including emotional and mental health. Genomic SNPs and brain circuitry abnormalities are linked. Instead of lumping conditions into broad categories such as depression, or ADHD, groupings are being redefined based on underlying genomics, …

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Genetics vs. Genomics

Genetics and genomics sound alike and are often used interchangeably, yet important scientific and clinical distinctions exist between these two scientific fields of study. The classical definition of genetics is the study of heredity, how characteristics and traits (phenotypes) of a living organism are transmitted from one generation to the next. This occurs via deoxyribonucleic …

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Genomics & Oxidative Stress

Oxidative Stress. A hot topic in helping to address many health issues related to our modern lifestyles. Do you recommend antioxidant supplements for your patients? Which antioxidants are right for them? How much do they need? Can patients get all antioxidants they need from food? How do you know? Genomic testing and analysis is able to answer …

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Your Personal Nutrient Requirements

Food is the foundation of healthy living. Now advances in genomic medicine are providing the tools you need to create personalized diet plans – with even more precision. Nutrients promote growth, development, and maintenance of the human organism, a complicated orchestration involving many biological systems. Nutrients can effect gene expressions that influence cell biology. Other ingredients …

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Protecting The Newborn

The Impact Of Endocrine Disruptors On The Developing Fetus   Dr. Thomas Zoeller and colleagues researched how CYP1A1 expression correlated with the expression of genes regulated by thyroid hormone. Cytochrome P450 CYP1A1 is one of the pathways that processes many of the toxins present in our environment today, including PCB’s and tobacco smoke. Some of …

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The Effect Of Air Pollution On Developing Brains

Is air pollution harming your loved ones?   A recent study found that the level of prenatal exposure to air pollutants, collectively known as polycyclic aromatic hydrocarbons, or PAHs, correlated with the amount of cortical white matter in the  the left side of the brain. The higher the levels of exposure, the greater the shrinkage …

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Time For One-Person Trials

Genomic Medicine requires a new approach   In Nature’s article “Time for one-person trials” Nicolas J. Schork commented that clinical trials and research studies ought to focus on the individual rather than an average response to a therapy. Nicholas Schork is currently director of human biology at the J. Craig Venter Institute in La Jolla, …

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